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Heat Shock Protein-Based Therapies

  • Book
  • © 2015

Overview

Editors:
  1. Alexzander A.A. Asea

    1. Professor and VD for Research Innovations, Deanship for Scientific Research,, University of Dammam, Dammam, Saudi Arabia

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  2. Naif N. Almasoud

    1. Deanship for Scientific Research and Preventive Dental Sciences Department, College of Dentistry, University of Dammam, Dammam, Saudi Arabia

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  3. Sunil Krishnan

    1. Gastrointestinal Translational Research, Center for Radiation Oncology Research, University of Texas MD Anderson Cancer Center, Houston, USA

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  4. Punit Kaur

    1. Department of Microbiology, Immunology & Biochemistry, Morehouse School of Medicine, Atlanta, USA

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  • Book contains chapters written by leaders in the field of heat shock protein (HSP) translational medicine
  • The book covers in depth novel treatments and therapeutic approaches by which scientists are harnessing heat shock protein (HSP)-based mechanisms to cure human disorders and diseases
  • Subjects covered in the book and accompanying tables and figures are well presented and easy for even lay people to understand

Part of the book series: Heat Shock Proteins (HESP, volume 9)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Heat Shock Protein HSP27-Based Therapies

    1. Front Matter

      Pages 1-1
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    2. HSP27 as a Therapeutic Target of Novel Inhibitors and Dietary Phytochemicals in Cancer

      • Elena Aréchaga-Ocampo, César López-Camarillo
      Pages 3-16

    3. Heat Shock Protein 27 (HSP27, HSPB1) Is Up-Regulated by Targeted Agents and Confers Resistance to Both Targeted Drugs and Chemotherapeutics

      • Daniele Musiani, John David Konda, Simona Pavan, Erica Torchiaro, Jessica Erriquez, Martina Olivero et al.
      Pages 17-25

    4. Heat Shock Proteins and Cancer: Plant Based Therapy

      • Evren Önay-Uçar
      Pages 27-48

  3. Heat Shock Protein HSP60-Based Therapies

    1. Front Matter

      Pages 49-49
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    2. Chaperonotherapy for Alzheimer’s Disease: Focusing on HSP60

      • Francesco Cappello, Antonella Marino Gammazza, Silvia Vilasi, Maria Grazia Ortore, Pier Luigi San Biagio, Claudia Campanella et al.
      Pages 51-76

    3. Secreted and Circulating Cell Stress Proteins in the Periodontal Diseases

      • Brian Henderson, Nikos Donos, Luigi Nibali, Frank Kaiser
      Pages 77-91

  4. Heat Shock Protein HSP70-Based Therapies

    1. Front Matter

      Pages 93-93
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    2. The Role of Heat Shock Protein 70 in Infection and Immunity

      • Jose Rey-Ladino, Abiola Senok, Abdullah Sarkar, Ahlam Al Shedoukhy
      Pages 95-117

    3. Potential Cytoprotective Effects of Heat Shock Proteins to Skeletal Muscle

      • John P. Vardiman, Philip M. Gallagher, Jacob A. Siedlik
      Pages 119-127

    4. Heat Shock Proteins in Triple-Negative Breast Cancer (TNBC) Treatment

      • Punit Kaur, Tarundeep Singh, Moses Galukande, Sunil Krishnan, Alexzander A. A. Asea
      Pages 129-149

    5. Heat Shock Proteins in Multiple Sclerosis Pathogenesis: Friend or Foe?

      • Rosaria Tinnirello, Giuseppina Turturici, Gabriella Sconzo, Walter Spinello, Alexzander A. A. Asea, Fabiana Geraci
      Pages 151-173

    6. New Indications for HSP90 and HSP70 Inhibitors as Antiviral Drugs

      • Matthew K. Howe, Timothy A. J. Haystead
      Pages 175-196

    7. Potential Applications of Nanoparticles for Hyperthermia

      • Caio César Quini, Sunil Krishnan
      Pages 197-216

  5. Heat Shock Protein HSP90-Based Therapies

    1. Front Matter

      Pages 217-217
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    2. Gene Therapy Against HSP90: Glucocorticoid Receptor-Assisted Cancer Treatment

      • Susanta Sekhar Adhikari, Sujan Kumar Mondal, Rajkumar Banerjee
      Pages 219-256

    3. Potential of HSP90 Inhibitors to Treat Neurofibromatosis-Related Tumors

      • Jeremie Vitte, Marco Giovannini
      Pages 257-271

    4. Role of Heat Shock Protein 90 in the Cause of Various Diseases: A Potential Therapeutic Target

      • Subhankar Paul
      Pages 273-287

    5. HSP90 Inhibitor-Based Strategies for Cancer Therapy: Advancing Toward Clinical Impact

      • David A. Proia, Richard C. Bates
      Pages 289-322
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Keywords

About this book

The book Heat Shock Protein-Based Therapies provides the most up-to-date review on new heat shock protein-based mechanisms used in the therapy and treatment of various human disorders and diseases, including cancer, muscular atrophy, neurodegenerative disorders (Alzheimer's Disease, Multiple Sclerosis) and infectious diseases (HIV, periodontal disease). Written by leaders in the field of heat shock protein research, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which mechanisms dependent on heat shock proteins are targeted. The chapters also provide answers as to HSP biological significance to the host. This book is a must read for graduate and postgraduates in the field of Drug Development, Biotechnology, Pharmaceutical Industry, Phytomedicine, Biology (plant and mammal), Biochemistry (pro- and eukaryotic), Oncology, Immunology, Microbiology, Exercise Medicine, Physiology, Inflammatory diseases, Autoimmunity, Pharmacology and Pathology.

Editors and Affiliations

  • Professor and VD for Research Innovations, Deanship for Scientific Research,, University of Dammam, Dammam, Saudi Arabia

    Alexzander A.A. Asea

  • Deanship for Scientific Research and Preventive Dental Sciences Department, College of Dentistry, University of Dammam, Dammam, Saudi Arabia

    Naif N. Almasoud

  • Gastrointestinal Translational Research, Center for Radiation Oncology Research, University of Texas MD Anderson Cancer Center, Houston, USA

    Sunil Krishnan

  • Department of Microbiology, Immunology & Biochemistry, Morehouse School of Medicine, Atlanta, USA

    Punit Kaur

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