Skip to main content
SpringerLink
Log in
Book cover

Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy

New Perspectives and Opportunities

  • Book
  • © 2016

Overview

Editors:
  1. Christopher D. Gregory

    1. MRC Centre for Inflammation Research, University of Edinburgh Queen’s Medical Research Institute, Edinburgh, United Kingdom

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Explores apoptosis as a pro-cancer as well as anti-cancer mechanism – from basic biology to oncology
  • Provides readers with new research on the multiple and diverse roles of apoptosis
  • Identifies novel therapeutic targets of apoptosis-based therapies

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 930)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (9 chapters)

  1. Front Matter

    Pages i-xvii
    Download chapter PDF

  2. Molecular Cell Biology of Apoptosis and Necroptosis in Cancer

    • Christopher P. Dillon, Douglas R. Green
    Pages 1-23

  3. Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis

    • Aaron M. Fond, Kodi S. Ravichandran
    Pages 25-49

  4. Microenvironmental Effects of Cell Death in Malignant Disease

    • Christopher D. Gregory, Catriona A. Ford, Jorine J. L. P. Voss
    Pages 51-88

  5. Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis

    • Catherine Dabrowska, Mingli Li, Yun Fan
    Pages 89-112

  6. Axl and Mer Receptor Tyrosine Kinases: Distinct and Nonoverlapping Roles in Inflammation and Cancer?

    • Ian Dransfield, Sarah Farnworth
    Pages 113-132

  7. Immunogenic Apoptotic Cell Death and Anticancer Immunity

    • Peter Vandenabeele, Katrien Vandecasteele, Claus Bachert, Olga Krysko, Dmitri V. Krysko
    Pages 133-149

  8. Cancer Cell Death-Inducing Radiotherapy: Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity

    • Benjamin Frey, Anja Derer, Heike Scheithauer, Roland Wunderlich, Rainer Fietkau, Udo S. Gaipl
    Pages 151-172

  9. Novel Approaches to Apoptosis-Inducing Therapies

    • Mike-Andrew Westhoff, Nicolas Marschall, Klaus-Michael Debatin
    Pages 173-204

  10. Killing Is Not Enough: How Apoptosis Hijacks Tumor-Associated Macrophages to Promote Cancer Progression

    • Andreas Weigert, Javier Mora, Divya Sekar, Shahzad Syed, Bernhard Brüne
    Pages 205-239

  11. Back Matter

    Pages 241-247
    Download chapter PDF
Back to top

Keywords

About this book

This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews.


Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.

Editors and Affiliations

  • MRC Centre for Inflammation Research, University of Edinburgh Queen’s Medical Research Institute, Edinburgh, United Kingdom

    Christopher D. Gregory

About the editor

Christopher D. Gregory is Professor of Inflammatory Cell Biology and the Deputy Director of the MRC Centre for Inflammation Research at the University of Edinburgh. Professor Gregory is an active research group leader in the fields of immunology, inflammation, and cancer with a particular interest in apoptosis. He has published over 100 scientific papers and has received over 6,950 citations.

Bibliographic Information

  • Book Title: Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy

  • Book Subtitle: New Perspectives and Opportunities

  • Editors: Christopher D. Gregory

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-319-39406-0

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016

  • Hardcover ISBN: 978-3-319-39404-6Published: 12 September 2016

  • Softcover ISBN: 978-3-319-81880-1Published: 22 April 2018

  • eBook ISBN: 978-3-319-39406-0Published: 24 August 2016

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVII, 247

  • Number of Illustrations: 1 b/w illustrations, 28 illustrations in colour

  • Topics: Cancer Research, Apoptosis, Molecular Medicine

Publish with us

Policies and ethics

Back to top

Search

Navigation