Overview
Covers the latest research accomplishments in heart valve biomechanics
Broadens readers’ understanding of novel concepts in valvular tissue viscoelasticity, collagen fibril/molecule mechanisms, hierarchical response of valvular tissue under deformation, cell-ECM interaction, and integrative multi-scale models
Maximizes reader insights into advanced computational modeling and simulation efforts of heart valve biomechanics driven by updated knowledge and high performance computing
Reviews exhaustively the key recent research into biomechanical investigations on the breakthrough approach/techniques such as tissue engineered heart valve/regeneration, transcatheter valve replacement, 3D imaging guided valve repair, and 3D bioprinting
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Table of contents(18 chapters)
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Native Heart Valve Function
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Heart Valve Disease and Treatment
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Computational Approaches for Heart Valve Function
Keywords
- GAGs in heart valve biomechanics
- automated heart valve bioreactors
- bending force in heart valve development
- biomechanics in mitral valve repairing
- biomechanics of myxoid mitral valves
- biomechanics of transcatheter heart valves
- biomechanics tissue engineered heart valves
- cardiac biomaterials
- computational modeling for the mitral heart valve
- computational modeling of heart valves
- decellularized heart valve scaffolds
- geometrical symmetry in bioprosthetic heart valve
- heart valve 3D printing
- heart valve calcification
- heart valve leaflets
- heart valve mechanotransduction
- heart valve tissue engineering
- mechanobiology of heart valve endothelial cells
- pregnancy-induced remodeling in heart valves
- viscoelasticity of heart valve tissues
About this book
This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.
Editors and Affiliations
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The Oden Institute and the Department of Biomedical Engineering, The University of Texas at Austin, Austin, USA
Michael S. Sacks
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The Department of Bioengineering, The University of Texas at Arlington, Arlington, USA
Jun Liao
About the editors
Dr. Jun Liao is an Associate Professor of Biomedical Engineering at the University of Texas at Arlington. Dr. Liao is an expert in tissue biomechanics and bioengineering, with interests in heart valves, cardiac muscle, and many other soft tissues. His research focus is to better understand the role of biomechanics in maintaining optimal tissue performance in physiological conditions and the biomechanical abnormality in diseased conditions, aiming to improving tissue replacement, repair, and medical intervention for diseases. Dr. Liao is a member of BMES, ASME, and AAAS and a Fellow of the American Heart Association.
Bibliographic Information
Book Title: Advances in Heart Valve Biomechanics
Book Subtitle: Valvular Physiology, Mechanobiology, and Bioengineering
Editors: Michael S. Sacks, Jun Liao
DOI: https://doi.org/10.1007/978-3-030-01993-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2018
Hardcover ISBN: 978-3-030-01991-4Published: 17 April 2019
eBook ISBN: 978-3-030-01993-8Published: 08 April 2019
Edition Number: 1
Number of Pages: XXV, 487
Number of Illustrations: 30 b/w illustrations, 95 illustrations in colour
Topics: Regenerative Medicine/Tissue Engineering, Biomedical Engineering and Bioengineering, Biotechnology