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Osteochondral Tissue Engineering

Nanotechnology, Scaffolding-Related Developments and Translation

  • Presents the latest biomaterials advances in OCTE, including natural and synthetic materials, and bioceramics-based materials for the repair of osteochondral defects
  • Covers the state-of-the-art in advanced processing methodology underlying tissue-engineered scaffolding development, such as additive manufacturing, 3D bioprinting, and supercritical fluid technology
  • Maximizes reader insights into commercially available products, translational research and turning research into products, and clinical trials and management of osteochondral lesions

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1058)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-ix
  2. Biomaterials Advances in Osteochondral Tissue

    1. Front Matter

      Pages 1-1
    2. Natural Origin Materials for Osteochondral Tissue Engineering

      • Walter Bonani, Weerasak Singhatanadgige, Aramwit Pornanong, Antonella Motta
      Pages 3-30
    3. Synthetic Materials for Osteochondral Tissue Engineering

      • Antoniac Iulian, Laptoiu Dan, Tecu Camelia, Milea Claudia, Gradinaru Sebastian
      Pages 31-52
    4. Bioceramics for Osteochondral Tissue Engineering and Regeneration

      • Sandra Pina, Rita Rebelo, Vitor Manuel Correlo, J. Miguel Oliveira, Rui L. Reis
      Pages 53-75
  3. Nanotechnology Approaches for Osteochondral Tissue Engineering

    1. Front Matter

      Pages 77-77
    2. Nanomaterials/Nanocomposites for Osteochondral Tissue

      • Ohan S. Manoukian, Connor Dieck, Taylor Milne, Caroline N. Dealy, Swetha Rudraiah, Sangamesh G. Kumbar
      Pages 79-95
    3. Nanofibers and Microfibers for Osteochondral Tissue Engineering

      • Zaida Ortega, María Elena Alemán, Ricardo Donate
      Pages 97-123
    4. Micro/Nano Scaffolds for Osteochondral Tissue Engineering

      • Albino Martins, Rui L. Reis, Nuno M. Neves
      Pages 125-139
  4. Osteochondral Tissue Scaffolding

    1. Front Matter

      Pages 141-141
    2. Layered Scaffolds for Osteochondral Tissue Engineering

      • Diana Ribeiro Pereira, Rui L. Reis, J. Miguel Oliveira
      Pages 193-218
  5. Advanced Processing Methodology

    1. Front Matter

      Pages 219-219
    2. Preparation of Polymeric and Composite Scaffolds by 3D Bioprinting

      • Ana Mora-Boza, María Luisa Lopez-Donaire
      Pages 221-245
    3. The Use of Electrospinning Technique on Osteochondral Tissue Engineering

      • Marta R. Casanova, Rui L. Reis, Albino Martins, Nuno M. Neves
      Pages 247-263
  6. Hydrogels Systems for Osteochondral Tissue Applications

    1. Front Matter

      Pages 279-279
    2. Gellan Gum-Based Hydrogels for Osteochondral Repair

      • Lígia Costa, Joana Silva-Correia, J. Miguel Oliveira, Rui L. Reis
      Pages 281-304
    3. Silk Fibroin-Based Hydrogels and Scaffolds for Osteochondral Repair and Regeneration

      • Viviana P. Ribeiro, Sandra Pina, J. Miguel Oliveira, Rui L. Reis
      Pages 305-325

About this book

This book reviews the most recent developments in the field of osteochondral tissue engineering (OCTE) and presents challenges and strategies being developed that face not only bone and cartilage regeneration, but also establish osteochondral interface formation in order to translate it into a clinical setting. Topics include nanotechnology approaches and biomaterials advances in osteochondral engineering, advanced processing methodology, as well as scaffolding and surface engineering strategies in OCTE. Hydrogel systems for osteochondral applications are also detailed thoroughly. Osteochondral Tissue Engineering: Nanotechnology, Scaffolding-Related Developments and Translation is an ideal book for biomedical engineering students and a wide range of established researchers and professionals working in the orthopedic field.

Editors and Affiliations

  • 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco, Guimarães, Portugal

    J. Miguel Oliveira, Sandra Pina, Rui L. Reis

  • Polymeric Nanomaterials and Biomaterials Department, Institute of Polymer Science and Technology, Spanish Council for Scientific Research (CSIC), Madrid, Spain

    Julio San Roman

About the editors

Dr. Joaquim Miguel Oliveira, BSc, PhD is a senior researcher “Investigador FCT 2012 and FCT 2015”, at the Portuguese Government Associate Laboratory ICVS/3B´s, University of Minho. Currently, he is a volunteer lecturer at the Faculty of Medicine, U. Porto and Dept. of Polymer Eng., UM. Since 2001, he has been involved in the development of biomaterials from natural origin for tissue engineering and regenerative medicine. His research activities have been increasingly focused on nanomedicine, stem cells and 3D in vitro models of disease.

Dr. Sandra Pina, MsC, PhD, is an assistant researcher at the Portuguese Government Associate Laboratory ICVS/3B’s, University of Minho. Her research interests include bioresorbable calcium phosphate-based nanomaterials and ionic incorporated calcium phosphates nanocomposites for internal fracture fixation in traumatology, cranio-maxillofacial, spine and orthopaedic surgery.

Prof. Rui L. Reis, PhD, DSc, Hon. Causa MD (UGranada) is the Vice-Rector for R&D, Director of the 3B’s Research Group and of the ICVS/3B´s, of UMinho – Portugal. He is the CEO of the European Institute of Excellence on TERM, and the President-elect of Global TERMIS (Tissue Engineering & Regenerative Medicine International Society) and the editor-in-chief of the JTERM.

Prof. Julio San Roman, PhD, is director of Instituto de Ciencia y Tecnología de Polímeros CSIC. His scientific activities are centred in the study and development of polymer systems for biomedical applications, and specifically in tissue engineering, polymer drugs and drug delivery systems.

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access