Skip to main content
Log in

Study of functional cosmetics based on stem cell technology

  • Review Article
  • Regenerative Medicine
  • Published:
Tissue Engineering and Regenerative Medicine Aims and scope

Abstract

Considering the steady increase in life expectancy slowing or reversing the deleterious effects of aging has garnered considerable interest. Accordingly, functional cosmetics based on stem cell technology (Stem cell cosmetics), which combine the anti-aging concept with high technology, is an emerging trend in the cosmetics industry. Stem cells possess self-renewal properties and the potency to differentiate. Therefore, stem cells are the most important cells in the skin, as they are the source for continuous regeneration of the epidermis. Stem cell cosmetics are developed based on stem cell technology, which involves using extracts or culture media of stem cells. However, cosmetics containing stem cells or their extracts have not been released into the market due to legal, ethical, and safety concerns. Meanwhile, plant stem cells, which circumvent these problems, are highly regarded in the cosmetics industry for improving culture technology. The European Union prohibits the use of cells, tissues, or products of human origin in cosmetics, whereas the Korea Food and Drug Association has allowed the use of sources originating from stem cell media in cosmetics since 2009. The global cosmetics market is worth more than 242 billion dollars; however, cosmetic companies across the world that are developing and launching stem cell cosmetics based on stem cell activators, culture extracts, and culture media are much more focused on the Korean cosmetic market.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Van Zant G, Liang Y. The role of stem cells in aging. Exp Hematol 2003; 31:659–672.

    Article  PubMed  Google Scholar 

  2. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663–676.

    Article  CAS  PubMed  Google Scholar 

  3. Murphy GF. Histology of the skin. In: Elder DE, Elenitsas R, Jaworsky C, Johnson BL Jr, editors. Lever’s Histopathology of the Skin. Philadelphia: Lippincott-Raven; 1997. p. 5–50.

    Google Scholar 

  4. Pincelli C, Marconi A. Keratinocyte stem cells: friends and foes. J Cell Physiol 2010;225:310–315.

    Article  CAS  PubMed  Google Scholar 

  5. Barthel R, Aberdam D. Epidermal stem cells. J Eur Acad Dermatol Venereol 2005;19:405–413.

    Article  CAS  PubMed  Google Scholar 

  6. Hughes KA, Alipaz JA, Drnevich JM, Reynolds RMM. A test of evolutionary theories of aging. Proc Natl Acad Sci USA 2002;99:14286–14291.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  7. Giangreco A, Qin M, Pintar JE, Watt FMM. Epidermal stem cells are retained in vivo throughout skin aging. Aging Cell 2008;7:250–259.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  8. Zouboulis CC, Adjaye J, Akamatsu H, Moe-Behrens G, Niemann C. Human skin stem cells and the ageing process. Exp Gerontol 2008;43:986–997.

    Article  CAS  PubMed  Google Scholar 

  9. Kwon OS, Yoo HG, Han JH, Lee SR, Chung JH, Eun HCC. Photoagingassociated changes in epidermal proliferative cell fractions in vivo. Arch Dermatol Res 2008;300:47–52.

    Article  PubMed  Google Scholar 

  10. Webb A, Li A, Kaur P. Location and phenotype of human adult keratinocyte stem cells of the skin. Differentiation 2004;72:387–395.

    Article  PubMed  Google Scholar 

  11. Braude P, Minger SL, Warwick RMM. Stem cell therapy: hope or hype. BMJ 2005;330:1159–1160.

    Article  PubMed Central  PubMed  Google Scholar 

  12. Choi EJ, Cho HB, Yoo HSS. Developments of culture media for human skin stem cell, and evaluation of efficacy of cosmetics containing culture media. Kor J Aesthet Cosmetol 2012;10:949–960.

    Google Scholar 

  13. Charlish, P. The fight against ageing: Stem cells offer new options. In: Prime. London; Informa Healthcare, 2012. p.62–67.

    Google Scholar 

  14. Cavezza A, Boulle C, Guéguiniat A, Pichaud P, Trouille S, Ricard L, et al. Synthesis of Pro-Xylane: a new biologically active C-glycoside in aqueous media. Bioorganic & Medicinal Chemistry Letters 2009;19:845–849.

    Article  CAS  Google Scholar 

  15. Kim WS, Park BS, Park SH, Kim HK, Sung JHH. Antiwrinkle effect of adipose-derived stem cell: activation of dermal fibroblast by secretory factors. J Dermatol Sci 2009;53:96–102.

    Article  CAS  PubMed  Google Scholar 

  16. Kim SM, Kim BHH. Anti-wrinkle effect of AdMSCs-CM in photoaging skin model of hairless mice. J Kor Soc Cosm 2011;17:689–696.

    Google Scholar 

  17. Jung ES, Lee JS, Lee JH, Huh SR, Kim YS, Hwang WT, et al. Effects of vegetable peptones on promotion of cell proliferation and collagen production. J Soc Cosmet Sci Kor 2009;35:65–72.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sang Mo Kwon.

Additional information

These authors contributed equally to the manuscript.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Choi, S.H., Yun, J. & Kwon, S.M. Study of functional cosmetics based on stem cell technology. Tissue Eng Regen Med 12 (Suppl 2), 78–83 (2015). https://doi.org/10.1007/s13770-014-0431-y

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13770-014-0431-y

Key Words

Navigation