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  • © 2014

Liver Immunology

Principles and Practice

  • Thoroughly revised, updated and a comprehensively leading title in the field

  • Covers bacterial, parasitic and viral infections of the liver, autoimmune liver disease, alcoholic and non-alcoholic fatty liver diseases, as well as transplantation issues

  • Developed by an international panel of leading experts

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Table of contents (31 chapters)

  1. Front Matter

    Pages i-xvi
  2. Introduction

    • Ian R. Mackay
    Pages 1-9
  3. Core Concepts in Immunology

    • Cliona O’Farrelly, Derek Doherty
    Pages 11-26
  4. The Geoepidemiology of Autoimmune Liver Disease

    • Carlo Selmi, Cecilia B. Chighizola, Angela Ceribelli, Maria De Santis, Pier Luigi Meroni, Renqian Zhong
    Pages 27-43
  5. Diagnostic Liver Immunology

    • Christopher L. Bowlus
    Pages 45-53
  6. The Liver as a Lymphoid Organ

    • Percy A. Knolle
    Pages 55-64
  7. Innate Immunity and Disorders of the Liver

    • Mathias Heikenwalder, Percy Knolle, Ulrike Protzer
    Pages 65-77
  8. The Liver and Immune Tolerance

    • Zhigang Tian, Cai Zhang, Zhe-Xiong Lian
    Pages 79-94
  9. Bacterial Infections in Liver

    • Eirini I. Rigopoulou, Daniel S. Smyk, Timoklia Orfanidou, Dimitrios P. Bogdanos, M. Eric Gershwin
    Pages 123-144
  10. The Diagnosis and Classification of Parasitic Diseases of the Liver

    • Shyamapada Mandal, Manisha Mandal
    Pages 145-158
  11. Viral Diseases of the Liver

    • Gadi Lalazar, Yaron Ilan
    Pages 159-171
  12. Hepatitis A: Immune Response and Virus Evolution

    • Rosa M. Pintó, Albert Bosch, Gerardo Kaplan
    Pages 173-189
  13. Hepatitis C

    • Mario U. Mondelli, Stefania Varchetta, Francesco Negro
    Pages 207-230
  14. Immunopathogenesis of Hepatitis D

    • Sebastian Lunemann, Jan Grabowski, Heiner Wedemeyer
    Pages 231-241
  15. Hepatitis E

    • Hiroki Takahashi, Mikio Zeniya
    Pages 243-252
  16. Primary Biliary Cirrhosis

    • Pietro Invernizzi, Patrick S. C. Leung, Xiong Ma, M. Eric Gershwin
    Pages 253-279
  17. Autoimmune Hepatitis

    • Diego Vergani, Rodrigo Liberal, Giorgina Mieli-Vergani
    Pages 281-300

About this book

Liver Immunology: Principles and Practice, Second Edition begins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters that provide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediated liver disease helps provide context for how these diseases affect the patient overall.  In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases --  primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome – are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others.  This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients.  Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Edition will again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases.  This volume will again be a must-read for clinicians at all levels, investigators and students.

Editors and Affiliations

  • Division of Rheumatology, Allergy and Clinical Immunology, University of California School of Medicine, Davis, USA

    M. Eric Gershwin

  • Medicine and Surgery, Baylor College of Medicine, Houston, USA

    John M. Vierling

  • Department of Gastroenterology, Hepatology and Endocrinology, Medical School of Hannover, Germany

    Michael P. Manns

Bibliographic Information

  • Book Title: Liver Immunology

  • Book Subtitle: Principles and Practice

  • Editors: M. Eric Gershwin, John M. Vierling, Michael P. Manns

  • DOI: https://doi.org/10.1007/978-3-319-02096-9

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media ,New York 2014

  • Hardcover ISBN: 978-3-319-02095-2Published: 02 December 2013

  • Softcover ISBN: 978-3-319-33087-7Published: 23 August 2016

  • eBook ISBN: 978-3-319-02096-9Published: 19 November 2013

  • Edition Number: 2

  • Number of Pages: XVI, 480

  • Number of Illustrations: 25 b/w illustrations, 92 illustrations in colour

  • Topics: Hepatology, Gastroenterology, Internal Medicine, Immunology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access