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Reducing Mortality in Critically Ill Patients

  • Book
  • © 2015

Overview

Editors:
  1. Giovanni Landoni

    1. Department of Anesthesia and Intensive care, IRCCS San Raffaele Scientifi c Institute, Milan, Italy

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  2. Marta Mucchetti

    1. Department of Anesthesia and Intensive care, IRCCS San Raffaele Scientific Institute, Milan, Italy

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  3. Alberto Zangrillo

    1. San Raffaele Hospital, Milan, Italy

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  4. Rinaldo Bellomo

    1. Department of Intensive Care, Austin Hospital, Heidelberg, Vic. 3084, Australia

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  • Identifies the techniques, strategies, and drugs proven by multi center randomized trials to influence survival in critically ill patients

  • Focuses on a specific procedure, device, or drug in each chapter

  • Includes helpful "how to do" sections and "key point" boxes

  • Written by acknowledged international experts

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-vi
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  2. Decision Making in the Democracy-based Medicine Era: The Consensus Conference Process

    • Massimiliano Greco, Marialuisa Azzolini, Giacomo Monti
    Pages 1-6

  3. Interventions that Reduce Mortality

    1. Front Matter

      Pages 7-7
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    2. Noninvasive Ventilation

      • Luca Cabrini, Margherita Pintaudi, Nicola Villari, Dario Winterton
      Pages 9-21

    3. Lung-Protective Ventilation and Mortality in Acute Respiratory Distress Syndrome

      • Antonio Pisano, Teresa P. Iovino, Roberta Maj
      Pages 23-29

    4. Prone Positioning to Reduce Mortality in Acute Respiratory Distress Syndrome

      • Antonio Pisano, Luigi Verniero, Federico Masserini
      Pages 31-38

    5. Tranexamic Acid in Trauma Patients

      • Annalisa Volpi, Silvia Grossi, Roberta Mazzani
      Pages 39-45

    6. Albumin Use in Liver Cirrhosis

      • Łukasz J. Krzych
      Pages 47-52

    7. Daily Interruption of Sedatives to Improve Outcomes in Critically Ill Patients

      • Christopher G. Hughes, Pratik P. Pandharipande, Timothy D. Girard
      Pages 53-59

  4. Interventions that Increase Mortality

    1. Front Matter

      Pages 61-61
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    2. Tight Glycemic Control

      • Cosimo Chelazzi, Zaccaria Ricci, Stefano Romagnoli
      Pages 63-71

    3. Hydroxyethyl Starch in Critically Ill Patients

      • Rasmus B. Müller, Nicolai Haase, Anders Perner
      Pages 73-78

    4. Growth Hormone in the Critically Ill

      • Nigel R. Webster
      Pages 79-82

    5. Diaspirin Cross-Linked Hemoglobin and Blood Substitutes

      • Stefano Romagnoli, Giovanni Zagli, Zaccaria Ricci
      Pages 83-91

    6. Supranormal Elevation of Systemic Oxygen Delivery in Critically Ill Patients

      • Kate C. Tatham, C. Stephanie Cattlin, Michelle A. Hayes
      Pages 93-101

    7. Does β2-Agonist Use Improve Survival in Critically Ill Patients with Acute Respiratory Distress Syndrome?

      • Vasileios Zochios
      Pages 103-109

    8. High-Frequency Oscillatory Ventilation

      • Laura Pasin, Pasquale Nardelli, Alessandro Belletti
      Pages 111-115

    9. Glutamine Supplementation in Critically Ill Patients

      • Laura Pasin, Pasquale Nardelli, Desiderio Piras
      Pages 117-122

  5. Updates

    1. Front Matter

      Pages 123-123
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    2. Reducing Mortality in Critically Ill Patients: A Systematic Update

      • Marta Mucchetti, Livia Manfredini, Evgeny Fominskiy
      Pages 125-132
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Keywords

About this book

This book describes the techniques, strategies, and drugs that have been demonstrated by multicenter randomized trials to influence survival in critically ill patients, defined as those who have acute failure of at least one organ, due to either a pathological condition or a medical intervention, and require intensive care treatment. Each chapter focuses on a specific procedure, device, or drug. The scope is accordingly wide, with coverage of topics as diverse as noninvasive mechanical ventilation, protective ventilation, prone positioning, intravenous salbutamol in ARDS, high-frequency oscillatory ventilation, mild hypothermia after cardiac arrest, daily interruption of sedatives, tranexamic acid, diaspirin cross-linked hemoglobin, albumin, growth hormone, glutamine supplementation, tight glucose control, supranormal oxygen delivery, and hydroxyethyl starch in sepsis. The topic selection was made using a democracy-based approach in which hundreds of specialists from dozens of countries expressed, via the web, whether they agreed with these topics and whether they used the techniques in their daily clinical practice. The clear text is supported by "how to do" sections and "key point" boxes that provide easily accessible practical information. The book will be of interest for a wide variety of specialists, including intensivists, emergency doctors, and anesthesiologists.

Reviews

“This summarized literature will continue to serve as a solid foundation and useful reference upon which to build in future. Specialists from areas of medicine that care for patients with critical illness will enjoy this book, especially those working in the intensive care unit. Experienced physicians will be comfortable with much of the subject matter and familiar with the landmark trails. … provides useful clinical summaries and practical application points that even physicians well versed in the literature will appreciate.” (Carmen Hrymak, Canadian Journal of Anesthesia, Journal canadien d'anesthésie, October, 2015)

“This is essentially a monograph of 15 evidence-based interventions that affect mortality in critical care patients. The book is the result of what the authors describe as a democracy-based consensus conference. It uses evidence-based medicine techniques to discuss seven interventions that reduce mortality and eight interventions that increase mortality. … The audience is critical care practitioners regardless of training background. The book also will be of value to medical students, residents, and fellows.” (Jeremy Scott Juern, Doody's Book Reviews, September, 2015)

Editors and Affiliations

  • Department of Anesthesia and Intensive care, IRCCS San Raffaele Scientifi c Institute, Milan, Italy

    Giovanni Landoni

  • Department of Anesthesia and Intensive care, IRCCS San Raffaele Scientific Institute, Milan, Italy

    Marta Mucchetti

  • San Raffaele Hospital, Milan, Italy

    Alberto Zangrillo

  • Department of Intensive Care, Austin Hospital, Heidelberg, Vic. 3084, Australia

    Rinaldo Bellomo

Bibliographic Information

  • Book Title: Reducing Mortality in Critically Ill Patients

  • Editors: Giovanni Landoni, Marta Mucchetti, Alberto Zangrillo, Rinaldo Bellomo

  • DOI: https://doi.org/10.1007/978-3-319-17515-7

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Softcover ISBN: 978-3-319-36726-2Published: 12 October 2016

  • eBook ISBN: 978-3-319-17515-7Published: 28 May 2015

  • Edition Number: 1

  • Number of Pages: VI, 140

  • Number of Illustrations: 1 b/w illustrations, 3 illustrations in colour

  • Topics: Intensive / Critical Care Medicine, Emergency Medicine, Pneumology/Respiratory System, Cardiology, Anesthesiology

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