Overview
Explores epigenetic landscape that occur in various cancer cells and the role of these changes in cancer initiation and progression
Discusses recent technological advancements that allow epigenetic alterations in cancer to be studied across the entire genome
Covers a spectrum of human cancers, including prostate, ovarian, breast, gastric, pancreatic, and more
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Table of contents(10 chapters)
About this book
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Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding RNAs expression are involved in a complex network of regulating expression of oncogenes and tumor suppressor genes and constitute an important event of the multistep process of carcinogenesis. Recent advances in the understanding of the epigenetic regulation and detailed information of these epigenetic changes in various cancers provide new avenues of advancements in diagnostics, prognostics, and therapies of this highly fatal disease.
Editors and Affiliations
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Department of Biological Sciences, Alabama State University, Montgomery, USA
Manoj K. Mishra
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School of Medicine, Washington University, St. Louis, USA
Kumar S. Bishnupuri
About the editors
Kumar S. Bishnupuri, Ph.D., is a Research Instructor in the Department of Medicine at Washington University School of Medicine. Dr. Bishnupuri has published over 16 articles, 4 book chapters, and 32 abstracts for conference symposia. He also serves as a scientific reviewer for several journals including Carcinogenesis, Frontiers in Bioscience, Cancer Biology and Therapy, Journal of Pathology, and more.
Bibliographic Information
Book Title: Epigenetic Advancements in Cancer
Editors: Manoj K. Mishra, Kumar S. Bishnupuri
DOI: https://doi.org/10.1007/978-3-319-24951-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-24949-0Published: 13 May 2016
Softcover ISBN: 978-3-319-79706-9Published: 26 May 2018
eBook ISBN: 978-3-319-24951-3Published: 04 May 2016
Edition Number: 1
Number of Pages: XI, 246
Number of Illustrations: 1 b/w illustrations, 11 illustrations in colour
Topics: Cancer Research, Gene Expression